PEG-MGF
£34.99
PEG-MGF
Growth Factor — Pegylated IGF-1 Splice Variant PEG-MGF is a pegylated form of Mechano Growth Factor, the splice variant of IGF-1 naturally upregulated by mechanical loading and muscle damage. Attaching polyethylene glycol (PEG) dramatically extends its otherwise very short half-life, allowing sustained activation of the satellite-cell repair pathway from a single dose. Base Compound: Mechano Growth Factor (MGF) Modification: PEGylated (extended half-life) Primary Research Focus: Muscle repair & satellite cell activation
PEG-MGF
Mechanism of Action
PEG-MGF activates satellite (muscle stem) cells, triggering their proliferation and differentiation into new muscle fibres — the same pathway through which mechanical loading naturally upregulates MGF expression in damaged tissue.
Extended Half-Life via PEGylation
Unmodified MGF has a plasma half-life of only minutes, limiting its research utility. Attaching a polyethylene glycol chain extends this considerably, allowing a single dose to sustain satellite-cell signalling over a much longer window.
Distinct from Systemic IGF-1
Because MGF and its PEGylated form act locally at the site of tissue damage rather than through systemic IGF-1 receptor activation, research interest has focused on localized muscle repair rather than the broader anabolic/mitogenic effects associated with IGF-1 LR3.
Research compound only — not licensed for human consumption or therapeutic use. Sold strictly for laboratory research purposes.
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