AOD 9604

AOD-9604 is a modified C-terminal fragment of human growth hormone developed to isolate lipolytic properties without stimulating IGF-1 or producing the anabolic side effects of full-length GH. Received GRAS status from the FDA as a food additive ingredient.

Mechanism of Action

AOD-9604 binds GH receptors in adipose tissue and acts through beta-3 adrenergic receptor stimulation and inhibition of lipogenic enzymes.

Lipolysis without IGF-1

Stimulates lipolysis while inhibiting lipogenesis — without elevating IGF-1, a key differentiator from full-length hGH relevant to chronic administration research.

Current Status: GRAS status (FDA) as food additive ingredient. Not approved as a drug.