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GHK-CU (Pen)

Price range: £44.99 through £48.99mg

GHK-Cu

Gly-His-Lys · Cu²⁺
GHK-Cu is a naturally occurring copper peptide first isolated from human plasma in 1973. It upregulates over 4,000 human genes, stimulates collagen synthesis, exerts antioxidant effects, and demonstrates broad anti-inflammatory activity. A well-established topical cosmetic ingredient with growing interest in systemic applications.
Discovery
1973, Loren Pickart
Genes Modulated
>4,000
Key Metal
Copper (Cu²⁺)
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NAD+ (Pen)

Price range: £48.99 through £68.99mg
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Retatrutide (Pen)

Price range: £49.99 through £113.99

Retatrutide

Metabolics & GLP-1 — Triple Agonist
GIP/GLP-1/GCG triple agonist peptide

Retatrutide is an investigational once-weekly triple agonist of the GIP, GLP-1, and glucagon receptors (triple G). In the Phase II SURMOUNT dose-finding trial, 12 mg weekly produced mean body weight loss of 24.2% at 48 weeks — the highest reported for any pharmacological agent in a controlled trial.

Mechanism:
GIP + GLP-1 + glucagon triple agonist
Stage:
Phase III trials (as of 2026)
Peak Phase II Weight Loss:
24.2% at 48 weeks

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Tirzepatide (Pen)

Price range: £54.99 through £74.99

Tirzepatide

Metabolics & GLP-1 — GIP + GLP-1 Dual Agonist

Tirzepatide is a first-in-class dual GIP and GLP-1 receptor agonist approved for type 2 diabetes and obesity. Clinical trials demonstrate superior weight loss compared to semaglutide, with up to 22.5% mean body weight reduction at 15 mg weekly dosing.

Mechanism
GIP + GLP-1 dual agonist
Half-Life
~5 days
Key Approval
FDA 2022 (Mounjaro®)
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