NAD+ (Pen)
Price range: £48.99 through £68.99mg
GHK-CU (Capsules)
Price range: £44.99 through £48.99mg
GHK-CU (Pen)
Price range: £44.99 through £48.99mg
GHK-Cu
Gly-His-Lys · Cu²⁺
GHK-Cu is a naturally occurring copper peptide first isolated from human plasma in 1973. It upregulates over 4,000 human genes, stimulates collagen synthesis, exerts antioxidant effects, and demonstrates broad anti-inflammatory activity. A well-established topical cosmetic ingredient with growing interest in systemic applications.
Discovery
1973, Loren Pickart
Genes Modulated
>4,000
Key Metal
Copper (Cu²⁺)
GHK-Cu
Mechanism of Action
GHK-Cu acts as a biological signal of tissue damage. Plasma levels decline from ~200 ng/mL at age 20 to ~80 ng/mL by age 60.
Gene Expression Modulation
Genome-wide microarray studies identify broad modulation of COL1A1, COL3A1, antioxidant enzymes, and anti-inflammatory pathways, appearing to reset expression toward younger phenotypes.
Copper Transport
Delivers Cu²⁺ to lysyl oxidase (collagen crosslinking) and Cu/Zn superoxide dismutase (antioxidant protection).
Exploratory reports: Small number of accounts from aesthetic and biohacking communities. Not peer-reviewed.
| Volume |
100mg ,50mg |
|---|
Vials (Peptides)
Pre-mixed Pens (Peptides)
Nasal Spray (Peptides)
Cream (Peptides)
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